Liverpool star Sadio Mane was among the goals for Senegal who, along with Nigeria and Tunisia, took significant steps on Tuesday toward qualifying for the 2022 World Cup in Qatar.
All three nations are seeded first in mini-leagues and have a maximum six points after two rounds having started with home victories over the lowest-ranked sides before winning away to the second seeds.
Another of the 10 four-team groups is led by lowly Tanzania, who scored off a penalty awarded after just five seconds when defeating Madagascar.
Reigning African Footballer of the Year Mane shrugged off being yellow-carded in Congo Brazzaville to complete a 3-1 victory by converting an 87th-minute penalty.