Bayern Munich suffered their first defeat since December 2019 as they were well beaten at Hoffenheim.
Bayern had won their past 23 matches, and were unbeaten in 32, a run that saw them win last season’s treble and the Uefa Super Cup on Thursday.
But Andrej Kramaric scored twice, including an injury-time penalty, to seal a famous Hoffenheim win.
The hosts are managed by Sebastian Hoeness, who was Bayern’s youth coach last season.